58  Wladis EJ, Bohnak CE, Law JJ, Adam AP, Rothschild MI, Pauze DR. Neutrophil-to-Lymphocyte Ratios Distinguish Idiopathic Orbital Inflammation From Orbital Infectious Disease. Ophthalmic Plast Reconstr Surg. (2023 Epub ahead of print)

57  Bossardi Ramos R, Martino N, Chuy D, Lu S, Zuo MXG, Balasubramanian U, Di John Portela I, Vincent PA, Adam AP. Shock drives a STAT3 and JunB-mediated coordinated transcriptional and DNA methylation response in the endothelium. J Cell Sci. (2023 Epub ahead of print)

56  Rodríguez-Sevilla P, Spicer G, Sagrera A, Adam AP, Efeyan A, Jaque D, Thompson SA. Bias in Intracellular Luminescence Thermometry: The Case of the Green Fluorescent Protein. Advanced Optical Materials. 11(11):2201664 (2023)

55  Wladis EJ, Wrzesinski SH, Rothschild MI, Adam AP. Emerging therapeutic options for periorbital and orbital cutaneous basal and squamous cell carcinomas. Orbit. 42(2):117-123 (2023)

54  Chebolu A, Ramos RB, Arunachalam T, Adam AP, Wladis EJ. SH2 domain-containing protein tyrosine phosphatase-2 is enriched in eyelid specimens of rosacea. Skin Health Dis. 3(1):e190 (2023)

53  Fitzgerald H, Bonin JL, Sadhu S, Lipscomb M, Biswas N, Decker C, Nabage M, Bossardi R, Marinello M, Mena AH, Gilliard K, Spite M, Adam A, MacNamara KC, Fredman G. The Resolvin D2-GPR18 Axis Enhances Bone Marrow Function and Limits Hepatic Fibrosis in Aging. bioRxiv. doi: 10.1101/2023.01.05.522881 (2023)

52  Martino N, Bossardi Ramos R, Chuy D, Tomaszek L, Adam AP. SOCS3 limits TNF and endotoxin-induced endothelial dysfunction by blocking a required autocrine interleukin-6 signal in human endothelial cells. Am J Physiol Cell Physiol. 323(2):C556-C569 (2022)

51  Wladis EJ, Arunachalam T, LaJoie JE, Lau KW, Adam AP. Myeloid differentiation factor 88 expression in eyelid specimens of rosacea. Orbit. 41(3):329-334 (2022)

50  Wladis EJ, Adam AP. Immune signaling in rosacea. Ocul Surf. 22:224-229 (2021)

49  Martino N, Ramos RB, Lu S, Leyden K, Tomaszek L, Sadhu S, Fredman G, Jaitovich A, Vincent PA, Adam AP. Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice. JCI Insight. 6(14):147280 (2021)

48  Lajoie JE, Lau KW, Adam AP, Wladis EJ. Cytotoxic T-Lymphocyte-Associated Protein-4 and Lymphocyte Activation Gene-3 Expression in Orbitally-Invasive Versus Nodular Basal Cell Carcinoma. Ophthalmic Plast Reconstr Surg. 37(3S):S109-S111 (2021)

47  O'Brien BJ, Singer HA, Adam AP, Ginnan RG. CaMKIIδ is upregulated by pro-inflammatory cytokine IL-6 in a JAK/STAT3-dependent manner to promote angiogenesis. FASEB J. 35(4):e21437 (2021)

46  Lu YW, Martino N, Gerlach BD, Lamar JM, Vincent PA, Adam AP, Schwarz JJ. MEF2 (Myocyte Enhancer Factor 2) Is Essential for Endothelial Homeostasis and the Atheroprotective Gene Expression Program. Arterioscler Thromb Vasc Biol. 41(3):1105-1123 (2021)

45  Hosseini Z, Marinello M, Decker C, Sansbury BE, Sadhu S, Gerlach BD, Bossardi Ramos R, Adam AP, Spite M, Fredman G. Resolvin D1 Enhances Necroptotic Cell Clearance Through Promoting Macrophage Fatty Acid Oxidation and Oxidative Phosphorylation. Arterioscler Thromb Vasc Biol. 41(3):1062-1075 (2021)

44  Balnis J, Adam AP, Chopra A, Chieng HC, Drake LA, Martino N, Bossardi Ramos R, Feustel PJ, Overmyer KA, Shishkova E, Coon JJ, Singer HA, Judson MA, Jaitovich A. Unique inflammatory profile is associated with higher SARS-CoV-2 acute respiratory distress syndrome (ARDS) mortality. Am J Physiol Regul Integr Comp Physiol. 320(3):R250-R257 (2021)

43  Spicer G, Gutierrez-Erlandsson S, Matesanz R, Bernard H, Adam AP, Efeyan A, Thompson S. Harnessing DNA for nanothermometry. J Biophotonics. 14(2):e202000341 (2021)

42  Overmyer KA, Shishkova E, Miller IJ, Balnis J, Bernstein MN, Peters-Clarke TM, Meyer JG, Quan Q, Muehlbauer LK, Trujillo EA, He Y, Chopra A, Chieng HC, Tiwari A, Judson MA, Paulson B, Brademan DR, Zhu Y, Serrano LR, Linke V, Drake LA, Adam AP, Schwartz BS, Singer HA, Swanson S, Mosher DF, Stewart R, Coon JJ, Jaitovich A. Large-Scale Multi-omic Analysis of COVID-19 Severity. Cell Syst. 2(1):23-40.e7 (2021)

41  Bossardi Ramos R, Adam AP. Molecular Mechanisms of Vascular Damage During Lung Injury. Adv Exp Med Biol. 1304:95-107 (2021)

40  Tubbesing K, Ward J, Abini-Agbomson R, Malhotra A, Rudkouskaya A, Warren J, Lamar J, Martino N, Adam AP, Barroso M. Complex Rab4-Mediated Regulation of Endosomal Size and EGFR Activation. Mol Cancer Res. 18(5):757-773 (2020)

39  Balnis J, Korponay TC, Vincent CE, Singer DV, Adam AP, Lacomis D, Geun Lee C, Elias JA, Singer HA, Jaitovich A. IL13-driven pulmonary emphysema leads to skeletal muscle dysfunction attenuated by endurance exercise. J Appl Physiol 128(1):134-148 (2020)

38  Godbout EE, Lau KW, Adam AP, Wladis EJ. Calcitonin Gene-Related Peptide in Blind, Painful Eyes. Ophthalmic Plast Reconstr Surg.36(3):241-242 (2020)

37  Wladis EJ, Weller BA, Adam AP. CD73 is Enriched in Cutaneous Carcinomas that Invade the Orbit. Ophthalmic Plast Reconstr Surg. 36(3):247-249 (2020)

36  Korponay TC, Balnis J, Vincent CE, Singer DV, Chopra A, Adam AP, Ginnan R, Singer HA, Jaitovich A. High CO2 downregulates skeletal muscle protein anabolism via AMPKα2-mediated depressed ribosomal biogenesis. Am J Respir Cell Mol Biol. 62(1):74-86 (2019)

35  Spicer G, Efeyan A, Adam AP, Thompson SA. Universal guidelines for the conversion of proteins and dyes into functional nanothermometers. J Biophotonics 12(9):e201900044 (2019)

34  Wilson CS, Bach MD, Ashkavand Z, Norman KR, Martino N, Adam AP, Mongin AA. Metabolic constraints of swelling-activated glutamate release in astrocytes and their implication for ischemic tissue damage. J Neurochem 151(2):255-272 (2019)

33  Wladis EJ, Lau KW, Adam AP. Nuclear Factor Kappa-B Is Enriched in Eyelid Specimens of Rosacea: Implications for Pathogenesis and Therapy. Am J Ophthalmol 201:72-81 (2019)

32  Thompson SA, Aggarwal A, Singh S, Adam AP, Tome JPC, Drain CM. Compromising the plasma membrane as a secondary target in photodynamic therapy-induced necrosis. Bioorg Med Chem 26(18):5224-5228 (2018)

31  Gao P, Wu W, Ye J, Lu YW, Adam AP, Singer HA, Long X. Transforming growth factor β1 suppresses proinflammatory gene program independent of its regulation on vascular smooth muscle differentiation and autophagy. Cellular signalling 50:160-170 (2018)

30  Thompson SA, Martínez IA, Haro-González P, Adam AP, Jaque D, Nieder JB, de la Rica P. Plug and Play Anisotropy-Based Nanothermometers. ACS Photonics 5(7):2676-2681 (2018)

29  Adam AP. A Potential New Mechanism Linking Type II Diabetes Mellitus and Alzheimer's Disease. BioEssays 40(6):e1800061 (2018).

28  Alsaffar H, Martino N, Garrett JP, Adam AP. Interleukin-6 promotes a sustained loss of endothelial barrier function via Janus kinase-mediated STAT3 phosphorylation and de novo protein synthesis. American journal of physiology. Cell physiology 314(5):C589-C602 (2018).

27  Adam AP, Zheng YM, Wang YX. The changes in endothelial cytoskeleton and calcium in vascular barrier breakdown: a response of ever-growing complexity. Pulmonary circulation 8(1):2045893218754854 (2018).

26  Wladis EJ, Lee JA, Carlson JA, Martino N, Adam AP. Programmed Death-1 Pathway in Orbital Invasion of Cutaneous Carcinomas. Ophthalmic plastic and reconstructive surgery 34(2):110-113 (2018).

25  Wladis EJ, Adam AP. Treatment of Ocular Rosacea. Survey of ophthalmology 63(3):110-113 (2018).

24  Lu YW, Lowery AM, Sun LY, Singer HA, Dai G, Adam AP, Vincent PA, Schwarz JJ. Endothelial Myocyte Enhancer Factor 2c Inhibits Migration of Smooth Muscle Cells Through Fenestrations in the Internal Elastic Lamina. Arteriosclerosis, thrombosis, and vascular biology 37:1380-1390 (2017).

23  Wladis EJ, Swamy S, Herrmann A, Yang J, Carlson JA, Adam AP. Activation of p38 and Erk Mitogen-Activated Protein Kinases Signaling in Ocular Rosacea. Investigative ophthalmology & visual science 58(2):843-848 (2017).

22  Garret JP, Lowery AM, Adam AP, Kowalczyk AP, Vincent PA. Src Regulation of endothelial barrier function by p120-catenin-VE-cadherin interaction. Mol Biol Cell 28:85-97 (2017).

21  Adam AP, Lowery AM, Martino N, Alsaffar H, Vincent P. Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-alpha: Crosstalk with p38 Signaling. PLoS ONE 11:e0161975 (2016).

20  Adam AP. Regulation of endothelial adherens junctions by tyrosine phosphorylation. Mediators of Inflammation, special issue "Recruitment of Immune Cells into Inflamed Tissues: Consequences for Endothelial Barrier Integrity and Tissue Functionality". Mediators Inflamm. 2015:272858 (2015).

19  Wladis EJ, Wang M, Bhoiwala D, Carlson A, Adam AP. Toll-like receptors and vascular markers in ocular rosacea. Ophthal Plast Reconstr Surg 290-293 (2013)

18  Shinde AV, Motiani RJ, Zhang X, Abdullaev IF, Adam AP, González-Cobos JC, Zhang W, Matrougui K, Vincent PA, Trebak M. STIM1 Controls Endothelial Barrier Function Independently of Orai1 and Ca2+ Entry. Science Signaling 6:ra18 (2013).

17  Wladis EJ and Adam AP. Current and emerging therapies for ocular rosacea. US Ophthalmic Review 7(2) (2013).

16  Alcaide P, Martinelli R, Newton G, Williams MR, Adam A, Vincent PA, Luscinskas FW. p120-catenin prevents neutrophil transmigration independently of Rho A inhibition by impairing Src dependent VE-cadherin phosphorylation. Am J Physiol: Cell Physiology 303: C385-C395 (2012).

15  Wladis EJ, Iglesias BV, Adam AP, Nazeer T, and Gosselin EJ. Toll-like Receptors in Idiopathic Orbital Inflammation. Ophthal Plast Reconstr Surg 28:273-276 (2012).

14  Wladis EJ, Iglesias BV, Adam AP, and Gosselin EJ. Molecular Biologic Assessment of Cutaneous Specimens of Ocular Rosacea. Ophthal Plast Reconstr Surg 28:246-250 (2012).

13  Adam AP, Sharenko AL, Pumiglia K, Vincent PA. Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. J Biol Chem 285:7045-7055 (2010).

12  Bajaj A, Zheng Q, Adam A, Vincent P, Pumiglia K. Activation of endothelial ras signaling bypasses senescence and causes abnormal vascular morphogenesis. Cancer Res 70:3803-3812 (2010).

11  Adam AP, George A, Schewe D, Bragado P, Iglesias BV, Ranganathan AC, Kourtidis A, Conklin DS, Aguirre-Ghiso JA. Computational identification of a p38SAPK-regulated transcription factor network required for tumor cell quiescence. Cancer Res 69:5664-5672 (2009).

10  Sequeira S, Ranganathan A, Adam A, Iglesias B, Farias E, Aguirre-Ghiso J., Inhibition of Proliferation by PERK Regulates Mammary Acinar Morphogenesis and Tumor Formation. PlosONE 2:e615 (2007).

9    Ranganathan A*, Adam A*, Aguirre-Ghiso J. Opposing Roles of Mitogenic and Stress Signaling Pathways in the Induction of Cancer Dormancy. Cell Cycle 5:1799-1807 (2006). (*equal contribution)

8    Ranganathan A*, Adam A*, Zhang L, Aguirre-Ghiso J. Tumor Cell Dormancy Induced by p38SAPK and ER-Stress Signaling. An Adaptive Advantage for Metastatic Cells? Cancer Biol & Therapy 5:729-735 (2006). (*equal contribution)

7    Ranganathan A, Zhang L, Adam A, Aguirre-Ghiso J. Functional Coupling of p38-Induced Up-regulation of BiP and Activation of RNA-Dependent Protein Kinase–Like Endoplasmic Reticulum Kinase to Drug Resistance of Dormant Carcinoma Cells. Cancer Res 66:1702-1711 (2006).

6    Mazzoni E, Adam A, Bal de Kier Joffé E, Aguirre-Ghiso J. Immortalized mammary epithelial cells overexpressing PKCgamma acquire a malignant phenotype and become tumorigenic in vivo. Mol Cancer Res 1:776-787 (2003).

5    Adam AP. Control extracelular de la apoptosis. Bol Inf Soc Arg Androl 11:44-46 (2002)

4    Adam AP. Apoptosis, in: Molecular Biology. Course of Continuous and Permanent Actualization in Clinical Oncology. Clinical Oncology Association, Postgraduate School of Health Sciences, Catholic University of Salta (2001)

3    Adam AP. Interaction between the Tumoral Cell and its Environment, in: Molecular Biology. Course of Continuous and Permanent Actualization in Clinical Oncology. Clinical Oncology Association, Postgraduate School of Health Sciences, Catholic University of Salta (2001)

2    Bal de Kier Joffé E, Adam A. Transformación celular y mecanismos de sobrevida regulados por la GTPasa RalA. Medicina 61:658-663 (2001).

1    Ladeda V*, Adam A*, Puricelli L, Bal de Kier Joffé E Apoptotic cell death is prevented by soluble factors present in the target organ of metastasis. Breast Cancer Res Treat 69:39-51 (2001). (*equal contribution)